https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Targeting eosinophils in respiratory diseases: biological axis, emerging therapeutics and treatment modalities https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46370 Wed 16 Nov 2022 08:45:58 AEDT ]]> Therapeutic potential of artemisia vulgaris: an insight into underlying immunological mechanisms https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44237 Artemisia vulgaris is a traditional Chinese herb believed to have a wide range of healing properties; it is traditionally used to treat numerous health ailments. The plant is commonly called mugwort or riverside wormwood. The plant is edible, and in addition to its medicinal properties, it is also used as a culinary herb in Asian cooking in the form of a vegetable or in soup. The plant has garnered the attention of researchers in the past few decades, and several research studies have investigated its biological effects, including antioxidant, anti-inflammatory, anticancer, hypolipidemic, and antimicrobial properties. In this review, various studies on these biological effects are discussed along with the tests conducted, compounds involved, and proposed mechanisms of action. This review will be of interest to the researchers working in the field of herbal medicine, pharmacology, medical sciences, and immunology.]]> Tue 11 Oct 2022 12:13:02 AEDT ]]> Curcumin-loaded niosomes downregulate mRNA expression of pro-inflammatory markers involved in asthma: an in vitro study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39066 in vitro release study, molecular simulations and was evaluated for in vitro anti-inflammatory activity. Results: Results showed that Nio-Curc had a mean particle size of 284.93 ± 14.27 nm, zeta potential of -46.93 and encapsulation efficacy of 99.62%, which demonstrates optimized physicochemical characteristics. Curcumin release in vitro could be sustained for up to 24 h. Additionally, Nio-Curc effectively reduced mRNA transcript expression of pro-inflammatory markers; IL-6, IL-8, IL-1β and TNF-a in immortalized human airway basal cell line (BCi-NS1.1). Conclusion: In this study, we have demonstrated that Nio-Curc mitigated the mRNA expression of pro-inflammatory markers in an in vitro study, which could be applied to treatment of asthma with further studies.]]> Tue 03 May 2022 12:13:38 AEST ]]> Formulation and characterization of glibenclamide and quercetin-loaded chitosan nanogels targeting skin permeation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42198 Thu 25 Aug 2022 11:34:49 AEST ]]> Immunological axis of curcumin-loaded vesicular drug delivery systems https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33591 Thu 22 Nov 2018 13:41:26 AEDT ]]> Molecular modulators of celastrol as the keystones for its diverse pharmacological activities https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38736 Thu 20 Jan 2022 16:12:34 AEDT ]]> Green synthesis and antibacterial potential of artemisia vulgaris extract in silver nanoparticles against wound bacteria https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49923 Thu 15 Jun 2023 11:20:40 AEST ]]> Anti-inflammatory and anticancer activities of Naringenin-loaded liquid crystalline nanoparticles in vitro https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49577 Mon 22 May 2023 10:51:01 AEST ]]> Assessing the potential of liposomes loaded with curcumin as a therapeutic intervention in asthma https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42611 Fri 26 Aug 2022 14:51:24 AEST ]]> Preparation, characterization and in-vitro efficacy of quercetin loaded liquid crystalline nanoparticles for the treatment of asthma https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42171 Fri 26 Aug 2022 08:02:59 AEST ]]> Molecular and immunological mechanisms underlying the various pharmacological properties of the potent bioflavonoid, rutin https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41789 Fri 12 Aug 2022 12:17:33 AEST ]]> Celastrol-loaded liquid crystalline nanoparticles as an anti-inflammatory intervention for the treatment of asthma https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42789 Fri 02 Sep 2022 14:04:09 AEST ]]>